Open access
Aug 2026
Physalin A protects against diabetes-like retinal neurodegeneration via autophagy, mitophagy, and antioxidant pathways in Drosophila melanogaster
PA confers neuroretinal protection in DR-like Drosophila by rebalancing apoptosis and autophagy, activating PINK1/parkin-mediated mitophagy, and strengthening antioxidant defenses, culminating in structural preservation and recovery of visual function.
Yan-Ru Xiao, Wei-Yong Lin, Wen-Zhen Lee et al.
· BioMedicine · 0 citations