Author

Wen-Wei Guan

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Aug 2026

Inhibition of ALPK1 attenuates myocardial ischemia-reperfusion injury in Nur77-deficient mice via suppressing XPO1-dependent pathway.

Despite being the initial intervention of choice, revascularization for myocardial ischemia-reperfusion (I/R) injury remains constrained, making the exploration of novel therapeutic targets imperative. Alpha-kinase 1 (ALPK1) knockdown mitigates ischemic brain injury, whereas its function in cardiac I/R injury requires...

Yue Liu, Ruisi Hu, Yan-Teng Wang et al. · Biochemical Pharmacology · 0 citations

Review Jul 2026

Single-cell resolution of skeletal muscle aging: Current paradigms and perspectives.

This work systematically summarize current progress in single-cell technology with respect to skeletal muscle aging, focusing on specific molecular characteristics and interaction networks of muscle fiber, satellite and immune cells during aging.

Yan-Teng Wang, Yichen Yang, Wen-Wei Guan et al. · Ageing Research Reviews · 0 citations