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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Wen-Wen Lu

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Review Open access Sep 2026

From synapse to sheath: how OPCs couple neural activity to adaptive myelination and behavioral plasticity

Oligodendrocyte precursor cells (OPCs) are abundant progenitor cells in the central nervous system. Unlike mature oligodendrocytes, OPCs form functional synapses with neurons and respond to both glutamatergic and GABAergic signals. Glutamate activates calcium-permeable AMPA receptors on OPCs, generating local Ca 2+...

Rui Tan, Wen-Wen Lu, Ai-Fen Yang et al. · 0 citations

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