Review
Open access
Aug 2026
XBP1 signaling from tumor metabolic stress to myeloid driven immunotherapy resistance (Review)
Targeting XBP1 may enhance the efficacy of existing therapies, particularly immune checkpoint blockade, by alleviating MDSC-mediated immunosuppression, offering a novel paradigm for understanding and reversing tumor immune escape.
Ziwei Chen, Jiaqi Wu, Wen-Xi Liu et al.
· International Journal of Mol... · 0 citations