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Wen-Xia Zhang

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Open access Sep 2026

Targeting PGAM1 Y119 phosphorylation resensitizes non-small-cell lung cancer to cisplatin therapy by promoting oxidative stress and DNA damage

Findings reveal a novel mechanism by which PGAM1 Y119 phosphorylation drives chemoresistance and suggest that targeting this phosphorylation event represents a potential therapeutic strategy to overcome cisplatin resistance in NSCLC.

Wen-Xia Zhang, Yan-Zhao Qu, Xin Wang et al. · 0 citations

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