Author

Wen-Xu Liu

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Case report Open access Aug 2026

A Functionally Constrained Immune Ecosystem in Microsatellite-stable Colorectal Cancer Resolved by Single-cell and Exome Profiling

T-cell abundance and immune effectiveness can be uncoupled in MSS CRC, and a molecular case report shows that T-cell abundance and immune effectiveness can be uncoupled in MSS CRC.

Wen-Xu Liu, Yi Zheng, Hao Wang et al. · Cancer Genomics & Proteomics · 0 citations

Open access Jul 2026

PAX5 modulates vascularization and contributes to neuroendocrine lineage transition during carcinoma progression.

It is found that PAX5, a neural/lymphatic transcription factor, contributed to neuroendocrine (NE) lineage transition, and targeting PAX5 and its downstream signaling may modulate lineage transitions responsible for treatment failure in both SCNCs and adenocarcinomas.

Ailing Wu, Yujie Hao, Xuemiao Yan et al. · Journal of Clinical Investig... · 0 citations