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Author

Wen-Xue Ma

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Review Open access Sep 2026

TREM2⁺ tumor-associated macrophages in cancer: context-dependent biology, biomarkers and precision immunotherapy.

Tumor-associated macrophages (TAMs) are abundant and functionally important components of the tumor microenvironment (TME), yet the molecular programs that distinguish pathogenic macrophage states from tissue-adaptive populations remain incompletely defined. Triggering receptor expressed on myeloid cells 2 (TREM2) has...

Xue-Jun Guo, Jing-Ya Yu, Xiao-Yan Lin et al. · 0 citations

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