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Author

Wenyan Zhu

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Open access Nov 2026

Identification of plasma biomarkers for chronic kidney disease by integrating proteomics and machine learning.

Background Chronic kidney disease (CKD) is a major global health burden, and early identification of individuals at risk remains challenging. This study aimed to identify plasma proteomic biomarkers associated with incident CKD and develop a machine learning-based prediction model integrating proteomic and clinical dat...

Shi-Qi Wang, Wen-Yan Zhu, Yu-Jia Zhang et al. · 0 citations
Open access Aug 2026

Leveraging expression quantitative trait loci information in single-cell resolution to identify cell-specific genes for Basal cell carcinoma

The authors' exploratory scTWAS using healthy donor PBMC-derived eQTLs uncovered cell-type-specific BCC associations missed by bulk analyses, providing hypothesis-generating insights into immune-related genetic effects in BCC, demonstrating how single-cell resolution can overcome signal dilution from cellular heterogen...

Min Du, Wenyan Zhu, Shiqi Wang et al. · 0 citations

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