Review
Open access
Aug 2026
Clonal evolution in gastrointestinal cancers: multi-omics insights into tumor heterogeneity, microenvironmental selection, and translational biomarkers
This work discusses the assumptions and sampling biases that constrain phylogenetic inference, the causal limits of cross-sectional tumor atlases, clonal hematopoiesis, and the incremental value of broad multi-omics over focused assays.
Wen-Yi Fan, Chun-Hong Zheng
· Frontiers in Oncology · 0 citations