Aug 2026
Activation of the KPNA2-mediated nuclear import of PPARα by KIF13B mitigates alcohol-associated liver steatosis.
BACKGROUND Alcohol-associated liver disease (ALD) is a major global health burden with no approved targeted therapies. Emerging evidence implicates kinesin family member 13B (KIF13B) in lipid metabolism, primarily in cardiovascular disease but its role in ALD remains unexplored. OBJECTIVE To investigate the role and...
Kai-Kai Lu, Si Mei, Lian-Xing Zhang et al.
· Gut · 0 citations