Author

Wen-Zhe Si

2 papers indexed here

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Review Open access Sep 2026

PSMD14 as a translational target in cancer and beyond: from deubiquitination mechanisms to drug resistance and precision therapy

The deubiquitinase PSMD14 (also known as RPN11 or POH1), a critical component of the JAB1/MPN/Mov34 metalloenzyme family, has emerged as a pivotal regulator of protein homeostasis through its deubiquitinating activity. While preclinical studies have extensively characterized PSMD14-mediated stabilization of oncogenic s...

Hong-Rui Liu, Liang Ma, Yi-Xuan Wang et al. · Cancer Drug Resistance · 0 citations

Review Open access Oct 2026

Immunomodulatory and Metabolic Effects of Ginsenosides Rg1/Rb1 in IBD, RA, and MASLD: Targeting Gut Microbiota–Autoimmunity Axis

Panax ginseng Meyer has been commonly used as a traditional herbal medicine in East Asia for millennia. Ginsenosides Rg1 and Rb1 are the primary pharmacologically active ingredients and exhibit broad therapeutic efficacy against immunometabolic disorders, including inflammatory bowel disease (IBD), metabolic dysfunctio...

Xin Mao, Zong-Xin Shao, Min Gao et al. · Microorganisms · 0 citations