Integrin beta-like 1 protects against liver injury by inhibiting ferroptosis in metabolic dysfunction-associated steatohepatitis.
BACKGROUND AND AIMS Metabolic dysfunction-associated steatohepatitis (MASH) is characterized by hepatic lipid accumulation, inflammation, and oxidative injury. However, the regulatory role of integrin beta-like 1 (ITGBL1) in MASH remains unknown. METHODS ITGBL1 knockout (KO) and liver-specific overexpressing mice wer...