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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

Wendy González

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2 papers indexed here

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Open access Oct 2026

Computationally Guided Design and Experimental Validation of ssDNA Aptamers Targeting the SARS-CoV-2 Spike Protein

Aptamer development has traditionally relied on iterative, labor-intensive experimental approaches. Recent advances in bioinformatics and computational power now enable the rational in silico design of high-affinity nucleic acid ligands, drastically reducing time and cost. Here, we present an integrated computational p...

José C. E. Márquez Montesinos, Ana Maria Bernardez, Yuliet Mazola et al. · 0 citations
Sep 2026

Molecular Basis of Dual-Site Engagement and Selectivity of CcoTx3-synth for hNaV1.5.

These findings provide the first structural and functional insights into the selective multisite engagement of CcoTx3-synth with hNaV1.5 and may guide the design of peptide therapeutics targeting cardiac channelopathies.

Erbio Díaz-Pico, Luciano Peña-Tejo, Pablo Barrías et al. · 0 citations

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