Wenjun Li

PPARα deficiency exacerbates atherosclerosis progressing through enhancing pTh17 cells-macrophage crosstalk.

Atherosclerosis (AS) is a chronic inflammatory disease driven by hypercholesterolemia and characterized by the accumulation of lipid-rich plaques within arterial walls. Although the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARα) is known to regulate lipid metabolism and inflammation, the prec...