Aug 2026
Downregulation of miR-33a-5p regulates TNF-α/NF-κB signaling and is associated with reduced diabetic neuropathic pain through targeting SIRT6.
BACKGROUND The pathogenesis of diabetic neuropathic pain (DNP) remains unclear, with neuroinflammation mediated by abnormal TNF-α/NF-κB pathway activation being a key factor. This study aims to elucidate how this pathway contributes to DNP. METHODS miR-33a-5p levels were measured via qPCR in the serum of diabetic pat...
Wenjun Li, Yimei Li, Yong-Xin Wang
· European Neurology · 0 citations