Review
Open access
Jul 2026
Methodological bias shapes the interpretation of the urinary microbiome in low-biomass systems
How factors such as sample collection methods, contamination dynamics, DNA extraction protocols, sequencing approaches, and bioinformatic pipelines shape microbial profiles and contribute to inconsistencies in microbiome–disease associations is examined.
Viviana Méndez-Sacta, Solmayra Agreda Orellana, Luz María Ayavaca-Tapia et al.
· Frontiers in Microbiology · 0 citations