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Author

William Joo

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Open access Aug 2026

Wake-activated neuronal populations that regulate sleep drive.

Prolonged wakefulness increases sleep drive and is normally compensated for by increased sleep1-3. This homeostatic regulation of sleep shapes our lives profoundly, but the underlying neural circuit mechanisms remain poorly understood. Here, we identify wake-activated neurons that regulate sleep drive in mice, using wh...

William Joo, Clare M. Diester, Vassilis Bitsikas et al. · 0 citations

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