Open access
Sep 2026
Dynamics of mutators of arbitrary dominance in humans
Recent findings in humans and other species have revealed the presence of “mutator” alleles that increase germline mutation rate across the genome. Such mutators are expected to be selected against because of the additional deleterious alleles that they generate, to a degree that will depend on how much they increase t...
Matin Saeidi, Guy Sella, Molly Przeworski et al.
· bioRxiv · 0 citations