Multi-Target Anti-Steatotic Effects of Andrographolide in MAFLD: Insights from Network Pharmacology and in vitro Study
Background Metabolic Associated Fatty Liver Disease (MAFLD) is a prevalent metabolic disorder with no effective approved pharmacotherapy. Andrographolide, a bioactive diterpenoid from Andrographis paniculata, has anti-inflammatory and antioxidant properties, but its mechanisms in MAFLD remain unclear. Methods An integr...