Open access
Sep 2026
Genetic Evidence for a Putative B Cell–Cholate Immunometabolic Axis in Pericarditis: A Mendelian Randomization Study
Background: Pericarditis is an inflammatory heart disease with unclear causal mechanisms. Immune dysregulation is implicated, but observational studies cannot reliably infer causality. Whether plasma metabolites mediate immune-pericarditis pathways remains unknown. Methods: A two-sample Mendelian randomization (MR) stu...
Yi-Fei Zhang, Wu-Xiao Yang, Xue-Wen Li
· Biomedicines · 0 citations