Author

Wulong Liang

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Open access Aug 2026

A multicohort machine-learning prognostic signature reveals inflammatory immune remodeling and statin sensitivity in glioblastoma

Introduction Glioblastoma (GBM) is characterized by substantial inter- and intra-tumoral heterogeneity. A robust multigene model may help address this heterogeneity and improve prognostic stratification. Methods We integrated 76 combinations derived from 10 machine-learning algorithms to develop a purificatory machine...

Zheng-Wei Xing, Han Yang, Yuan Lyu et al. · Frontiers in Oncology · 0 citations

Aug 2026

MLN4924 Enhances RSL3-Induced Ferroptosis Sensitivity in Glioblastoma via Inhibiting the STAT3/GPX4 Axis.

GPX4 is identified as the principal mediator of MLN4924-induced ferroptosis and dual targeting of GPX4 transcription and activity represents a promising therapeutic strategy for GBM, establishing that dual targeting of GPX4 transcription and activity represents a promising therapeutic strategy.

Zhou Jing, Fangyuan Wang, Hao Li et al. · Carcinogenesis · 0 citations