Review
Open access
Jul 2026
Protein lactylation in cancer: principles, programmes and therapeutic opportunities.
Inhibition of lactate metabolism markedly attenuates tumor-associated lactylation and exhibits substantial synergistic efficacy when combined with other anti-tumor therapies, providing an important conceptual and theoretical foundation for the development of novel cancer therapeutic strategies targeting protein lactyla...
X. Bu, Xinyue Yu, Jie Wang et al.
· Molecular Cancer · 1 citation