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X. Lin

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Review Open access Aug 2026

A novel bone and cancer cells co-culture methodology to model breast cancer metastasis to bone ex vivo

An ex vivo co-culture protocol for modeling bone metastasis that enables direct investigation of cancer cell interactions with the native bone and marrow microenvironment and enables high-throughput functional interrogation of cancer colonization in a complex microenvironment is presented.

Ricardo Romero-Moreno, Courtney L. Flatt, Madeline P. Sheeley et al. · 0 citations

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