Review
Open access
Oct 2026
Regulatory T cell dysfunction and therapeutic advances in rheumatoid arthritis, psoriasis, vitiligo, and systemic lupus erythematosus.
Regulatory T cells (Tregs) are a critical immunosuppressive subset of CD4+ T cells, whose lineage stability and suppressive function rely on the transcription factor FOXP3. Within inflamed tissue microenvironments, Tregs maintain immune homeostasis and preserve tissue integrity via multiple mechanisms, including secret...
Yan-Yang Liang, Hai-Yang Feng, Ying Wang et al.
· Frontiers in Immunology · 0 citations