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Open access Aug 2026

An Integrative Multimodal Model for Early Diagnosis of Dementia and Differential Diagnosis of Alzheimer's Disease Using Neuroimaging, Polygenic Risk, and Cognitive Assessments

Multimodal integration of cognitive, neuroimaging, and polygenic data in the MHS-RWD tool yields strong discrimination for both early diagnosis of dementia and AD differential diagnosis, which could support etiologically informed dementia decisions in real-world settings, with potential utility in primary care.

T. T. Filiz, V. Fominykh, K. Persson et al. · 0 citations
Review Open access Jul 2026

Sex-Specific Dietary Inflammation and Metabolic Syndrome Across Three Nations: Cross-National IPD Harmonisation with Observational and Supportive Genetic Evidence for the Inflammatory Pathway (Diet-Attributable Component Bounded at OR=1.001-1.013)

A critical finding is the construct validity failure of the 20-item DII in non-Western dietary contexts, underscoring the need for population-specific inflammation metrics.

S. Huang, X. Wang · 0 citations

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