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Oct 2026

Abstract B046: Integrating genetic ancestry and social determinants of health reveals context-dependent genetic susceptibility to laryngeal cancer

Laryngeal cancer is characterized by persistent racial disparities. Self-identified race and ethnicity (SIRE) may not adequately capture biologically relevant population heterogeneity. Because SIRE conflates biological ancestry with social and environmental exposures, we examined how genetic susceptibility varian...

Joab O. Odera, Morgan C. Byrd, O. Osazuwa-Peters et al. · 0 citations

Incorporating LLM Embeddings for Variation Across the Human Genome

This work presents one of the first systematic frameworks to generate genetic variant-level embeddings across the entire human genome, using curated annotations from FAVOR, ClinVar, and the GWAS Catalog to construct functional text descriptions for 8.9 billion possible variants.

Hongqian Niu, Jordan G. Bryan, Jacob Williams et al. · 1 citation

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