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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Xi-Lin Chen

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Open access Sep 2026

Sleep Deprivation Induces Glial Dysfunction, Synaptic Loss, Metabolic Imbalance, and Cognitive Impairment in 12‐Month‐Old Mice: Protective Effects of D30

ABSTRACT Background Sleep deprivation (SD) has been increasingly implicated in age‐related cognitive decline. However, the mechanisms linking SD duration to progressive disruption of glial homeostasis, synaptic vulnerability, and metabolic dysregulation remain poorly defined. Methods We employed 12‐month‐old Thy1‐EGFP...

Xue-Yan Liu, Hui-Ling Lin, Jian Zhong et al. · 0 citations

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