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Author

Xi-Nan Shi

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Open access Aug 2026

Polyphyllin I Orchestrates Autophagy to Reprogram the Tumour Immune Microenvironment and Abrogate Cisplatin Resistance in Non-Small Cell Lung Cancer.

OBJECTIVE This study aims to elucidate the molecular mechanisms by which Polyphyllin I (PPI), a potent steroidal saponin, attenuates non-small cell lung cancer (NSCLC) progression via mechanistic reprogramming of an autophagy-dependent immunogenic response. METHODS Integrated in vitro (A549, H460) and in vivo (LLC xe...

Zongxu Liu, Yanping Li, Shumin Li et al. · 0 citations

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