Author

Xia He

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Review Open access Aug 2026

Sequential antibody induction for immune tolerance in clinical organ transplantation: a feasibility review of immunosuppressant withdrawal protocols

This review systematically examines the immunological rationale and major clinical strategies (T-cell depletion, costimulation blockade, mixed chimerism, and regulatory cell therapy) and proposes four novel sequential regimens with explicit evidence levels based on efficacy, safety, and feasibility.

Ya-Chao Li, Fu-Xia Chen, Xia He et al. · Frontiers in Immunology · 0 citations

Jul 2026

Parallel 4-1BB Signaling in Dual DLL3/CD56-Targeting CAR-T Cells Triggers Adaptive Proliferation and Functional Persistence to Eradicate Small Cell Lung Cancer.

These findings establish a clinically translatable combinatorial framework to enhance the efficacy and durability of CAR-T therapy in solid tumors and establish a clinically translatable combinatorial framework to enhance the efficacy and durability of CAR-T therapy in solid tumors.

Yan-Na Lei, Di-Yuan Qin, Yan He et al. · Cancer Research · 0 citations