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Xia Jiang

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Open access Sep 2026

Integrative Genomic and Functional Investigation of the Multi-Layered Genetic Architecture Between Anorexia Nervosa and Bone Loss.

OBJECTIVE Bone loss is a severe and often irreversible complication of anorexia nervosa (AN), yet the genetic mechanisms underlying this comorbidity remain underexplored. This study focuses on constructing a comprehensive genetic architecture between AN and estimated calcaneal bone mineral density (eBMD). METHOD We a...

T. Han, Yu-Ke Wang, Yi Dang et al. · 0 citations
Review Open access Sep 2026

Sugar-sweetened beverages consumption and the risk of depression in youth: A systematic review and meta-analysis of observational studies.

BACKGROUND Research on the association between sugar-sweetened beverages (SSBs) and depression has advanced, but most studies are cross-sectional and focus on adults. This meta-analysis assesses their association in youth using observational data. METHODS We searched Ovid Cochrane, Ovid Embase, Ovid Medline, and Psyc...

Ping Wang, Jia-Wei Liu, Y. Ju et al. · 0 citations
#diffusion models Open access Sep 2026

Mortality-trained MRI brain age acceleration mediates sex-specific associations between health-related phenotypes and incident dementia

Brain age acceleration (BAA) has emerged as a promising neuroimaging marker of brain health and neurodegeneration. However, most existing brain age models are trained to predict chronological age, which may not be the most clinically relevant target. In this study, we instead developed a brain age model trained o...

Ke Jiang, Lei Lin, Tao Zhang et al. · 0 citations
Open access Jul 2026

Combined sleep behaviors, mediating biomarkers, and incident vascular complications among individuals with type 2 diabetes: A prospective study in UK Biobank

A healthy sleep pattern is associated with lower risks of vascular complications in type 2 diabetes, independent of traditional risk factors, and the association with microvascular complications is modified by diabetes severity.

Yanqiu Zou, Xia Jiang, Jin-Yu Zhou et al. · 0 citations
Open access Aug 2026

Metabolic Profiling of Epigenetic Aging and Its Associations With Aging‐Related Phenotypes and Modifiable Lifestyle Factors

These five metabolic signatures of epigenetic age acceleration (EAA) exhibited significant associations with aging‐related phenotypes including higher disease risk, poorer health status, and adverse clinical indicators including Gallstones, chronic kidney disease, and hepatitis.

Xun-Ying Zhao, Tian-Pei Ma, Mao-Yao Xia et al. · 0 citations
Aug 2026

Metabolomic Profiling of Telomere Length: Associations with Aging-related Phenotypes and Modifiable Lifestyle Factors in Chinese Older Adults.

The Met-TL may serve as a promising biomarker of cellular aging, particularly in identifying liver dysfunction, facilitating the development of personalized aging monitoring and anti-aging intervention strategies.

Tian-Pei Ma, Xun-Ying Zhao, Ke Jiang et al. · 0 citations

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