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Xia Xiao

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Open access Aug 2026

An IgG-like fusion protein comprising an anti-Spike S2 antibody and ACE2 exhibits potent and broad neutralization against SARS-CoV-2 and variants of concern

A bispecific fusion protein with potent broad-spectrum neutralizing activity against SARS-CoV-2 variants is developed and provides a promising strategy for next-generation coronavirus biologics.

Zhi-Zhong Wei, Ximing Liu, Kailun Wang et al. · 0 citations
Open access Aug 2026

The EV-A71 RNA-binding protein Matrin 3 facilitates viral replication by stabilizing viral RNA via ZDHHC20-mediated palmitoylation.

A mechanistic pathway by which EV-A71 co-opts MATR3 through condensate formation and palmitoylation to stabilize its genomic RNA and promote viral replication is delineated, and a comprehensive profiling dataset of host proteins associated with EV-A71 RNA is provided.

Xiaoyan Zuo, Yong-Jun Chen, Xia Xiao et al. · 0 citations

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