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Xian Guo

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Open access Oct 2026

Integrated 4D-DIA proteomic and transcriptomic profiling delineates the molecular trajectory of yak testicular development

Normal testicular development is essential for sustaining male fertility in livestock, yet the underlying molecular regulatory mechanisms remain poorly understood, particularly in environmentally adapted breeds such as the yak. In this study, we employed an integrated 4D-DIA proteomic and transcriptomic strategy...

Li-Yan Hu, Meng-Li Cao, Shao-Ke Guo et al. · 0 citations
Open access Oct 2026

Genome-Wide Association Study of Body Measurement Traits at Birth in Cattle

Hexi cattle are an indigenous beef breed developed through multigenerational crossing of Simmental and Mongolian cattle, exhibiting exceptional adaptability to arid and semi-arid environments alongside robust growth performance. To investigate the genetic architecture underlying early growth traits, we conducted a GWAS...

Xin-Lu Wang, Wei-Guo Ju, Xiao-Ming Ma et al. · 0 citations
Open access Aug 2026

Comprehensive analysis of differential mRNA, lncRNA and circRNA and their ceRNA network in the Longissimus Dorsi Muscle of Jerseyyak in response to dietary protein levels

Introduction The Jersey-yak, a hybrid offspring of Jersey cattle and yak, exhibits characteristics such as strong adaptability, rapid growth and development, and outstanding production performance. Therefore, Jersey-yaks were fed diets with different crude protein (CP) levels (0%, 15.16%, and 17.90% CP, respectively),...

Guo-Wu Yang, Bin Ma, Y. La et al. · 0 citations
Open access Sep 2026

Genetic Variation and Haplotype Structure of CFAP299 and PRDM8 Associated with Fiber Yield and Hair Length Traits in Tianzhu White Yak

Fiber yield and hair length are important economic traits in Tianzhu White Yak. However, the genetic variants associated with fiber production performance in this breed remain insufficiently characterized. This study aimed to investigate the associations of single nucleotide polymorphisms (SNPs) in the CFAP299 and PRDM...

Yi-Cheng Liu, Xue-Dong Qi, Yongfu La et al. · 0 citations
Open access Sep 2026

Polymorphisms in CALCRL and MPC1 Genes and Their Associations with Growth Traits in Tianzhu White Yaks

Simple Summary Tianzhu white yaks are multipurpose livestock that support pastoral communities on the Qinghai–Tibet Plateau, where animals must cope with cold, low oxygen, and seasonal feed shortages. Genetic variants associated with body weight and body size may help improve genetic evaluation. In this study, 536 Tian...

Tian Gu, Xue-Dong Qi, Yongfu La et al. · 0 citations
Review Open access Aug 2026

The Role of Cold Shock Protein (CSP) Gene Family in Yak (Bos grunniens) for High-Altitude Adaptation: Genome-Wide Identification and Analysis.

A genome-wide identification and comparative analysis of the CSP gene family in yak is performed primarily using bioinformatics approaches based on publicly available genomic and transcriptomic datasets, along with a preliminary validation of their differential expression under cold and hypoxic stress.

Yixuan Tang, Yufei Zan, Ziqiang Ding et al. · 0 citations

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