Author

Xian-Long Zhang

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Sep 2026

Machine Learning-Assisted Multiplexed and Ultrasensitive Biosensing of Pathogenic Bacteria based on a Tt Ago-Powered Autocatalytic Nucleic Acid Circuit and Encoded SERS Tags

Programmable nucleases have obtained widespread application in the field of pathogen detection, yet they face considerable challenges in multiplex detection. As a sister technology to CRISPR/Cas systems, Argonaute proteins (Ago) possess programmability, sequence specificity, and multi-turnover capability, rendering t...

Xi-Ru Zhang, Man-Yan Qiu, Jia-Xi Huang et al. · Analytical Chemistry · 0 citations

Review Sep 2026

Carbohydrate polymer-based nanoarmor systems for probiotic gastrointestinal delivery: Strategies, applications, and perspectives.

Probiotics have shown great potential for promoting human health. However, their viability is reduced during gastrointestinal transit owing to harsh conditions (e.g., gastric acidity, bile salts, and digestive enzymes). Recently, nanoarmor-based encapsulation has attracted extensive attention for probiotic protection a...

Zhuang Song, Yi-Na Zhao, Xiao-Feng Hu et al. · Carbohydrate Polymers · 0 citations