Jul 2026
cPKCγ facilitates the apoptosis of mouse GC-1 spg cells by regulating the mitophagy via inhibiting the UCHL1/HIF‑1α axis.
Collectively, cPKCγ exacerbates spermatogonial apoptosis by repressing UCHL1/HIF-1α-dependent mitophagy, suggesting a potential molecular mechanism for spermatogonial vulnerability under cryptorchidism-related heat stress.
Huajun Yang, You-You Tian, Shaoguang Feng et al.
· Systems Biology in Reproduct... · 0 citations