Author

Xiang Chen

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Open access Sep 2026

TLR3 Overexpression Attenuates D-GalN/LPS-Induced Acute Liver Injury and Is Associated With AMPK Phosphorylation, Autophagy-Related Changes, and IRF3 Upregulation

TLR3 overexpression significantly alleviated acute liver injury and apoptosis in GalN/LPS-induced acute liver injury models, and was associated with increased AMPK phosphorylation and elevated IRF3 expression in both in vivo and in vitro experiments.

Yi Zhang, Jun Zou, Xiang Chen · Discover medicine · 0 citations