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Author

Xiang Chen

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Open access Aug 2026

Skeletal Muscle–Derived Extracellular Vesicles During Eccentric and Concentric Exercise Promote Muscle Regeneration After Injury

EE facilitates muscle repair more effectively than CE by promoting the release of mEVs enriched in pro‐regenerative lipid metabolites, which suggests EE‐mEVs as a promising biological therapeutic strategy for muscle injury, particularly in cases where exercise is not feasible.

Yining Zhou, Xiaoyan Shao, Pan Zhang et al. · 0 citations
Jul 2026

Ligand-Mediated Reprogramming Redirects Liver-Tropic Ionizable Lipid Nanoparticles for Lung-Selective mRNA Delivery.

A ligand-mediated lipid reprogramming approach that repurposes chemically defined, liver-tropic, ionizable lipids (lipidoids) for mRNA delivery beyond the liver, and achieves outperformed efficacy and therapeutic potential in lung-specific genome editing relative to SORT-constructed 2-t6b LNP system.

Zhuxiao Gu, Xinhong Xiong, Xiang Chen et al. · 0 citations

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