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Author

Xiang Gao

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Aug 2026

TL1A(TNFSF15)-ENO1 axis promotes osteoarthritis by disrupting redox homeostasis via the PI3K/AKT pathway.

OBJECTIVE Osteoarthritis (OA) is characterized by cartilage degeneration, oxidative stress, and chondrocyte senescence. This study investigated whether TL1A promotes OA through ENO1-associated redox, senescence and PI3K-AKT signaling mechanisms. METHOD Human paired OA cartilage, primary chondrocytes, and mouse age-as...

Xiang Gao, Jun-Tan Li, Chang-Yu Yin et al. · 0 citations

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