Revealing the toxicological effects and mechanisms of tris(1-chloro-2-propyl) phosphate exposure on osteoarthritis based on network toxicology, machine learning, and molecular docking
Osteoarthritis (OA) is a degenerative disease affecting all joints in the body, impacting over 500 million people globally and imposing a significant healthcare burden. Tris(1-chloro-2-propyl) phosphate (TCPP), one of the widely used organophosphate flame retardants (OPFRs), exhibits notable environmental and biologica...