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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Xiang-Ran Wang

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Oct 2026

Turning DNAzyme into a Stitch-to-Activate Biosensor for Single-Base-Resolution Molecular Diagnostics

The catalytic core of DNAzymes is highly sensitive to local structural perturbations. Conventional DNAzyme-based SNV sensing mainly relies on differences in hybridization stability between matched and mismatched targets. Here, we position the SNV immediately adjacent to the catalytic-core reconstitution junction of a...

Xiang-Ran Wang, Xin-Xin Lu, Zheng-Quan Yang et al. · 0 citations

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