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Author

Xiang Yu

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Open access Sep 2026

Shank3 mutation disrupts affective touch encoding in the dorsal medial prefrontal cortex of Beagle dogs

Individuals with autism spectrum disorder (ASD) often show aversion to affective touch (AT). However, the neural mechanism of this abnormality in cortices remains poorly understood probably due to the lack of effective animal models. Here, we used a canine model to address this issue by leveraging the intimate dog-huma...

Yan-He Zhou, Yue He, Min-Na Dan et al. · 0 citations
Review Aug 2026

Heterogeneity in autism - challenges and opportunities.

Report from the 2021 Lancet Commission on autism recommends that research should focus on improving quality of life through personalized assessment and intervention, and that gene therapy may offer future therapeutic options.

Xiang Yu · 0 citations

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