Open access
Sep 2026
Causal roles of phenotypic age and metabolic health on dementia: a Mendelian randomisation and structure learning study
Background Phenotypic age acceleration (PhenoAgeAccel), derived from PhenoAge, and MetaboHealth are composite exposures of biological ageing and metabolic health associated with dementia-related outcomes. Whether these associations are causal and reflect the exposures, constituent biomarkers, or both remains unclear. M...
A. Baousi, K. Dobinda, J. Zhu et al.
· medRxiv · 0 citations