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Xiang-Yu Li

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Open access Sep 2026

Structural and Mechanistic Basis of Dual Substrate Promiscuity in the Acyltransferase AntB Enables Late-Stage Diversification of Natural Products.

Biocatalytic regioselective acylation is a powerful strategy for diversifying natural products and optimizing their pharmacological properties. Compared with plant acyltransferases (ATs), bacterial tailoring ATs remain poorly understood. AntB from the antimycin pathway was previously reported to possess acyl-donor prom...

Meng-Meng Zheng, Yu-Han Dai, Xiang-Yu Li et al. · 0 citations

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