Review
Open access
Sep 2026
Endothelial system dysregulation underlies keloid development and therapeutic targeting
Cutaneous keloids are pathological scars resulting from aberrant wound healing, characterized by infiltrative growth beyond the original wound margins and a failure to regress spontaneously. Although traditionally attributed to excessive extracellular matrix deposition and fibroblast proliferation, emerging evidence un...
Yong-Xin Yu, Jue-Xian Zhu, Long-Guo Ma et al.
· Frontiers in Cell and Develo... · 0 citations