Jul 2026
Geometrically adaptive hydrogel attenuates osteoarthritis via metabolic reprogramming and defect sealing.
Effective treatment for osteoarthritis (OA) remains challenging because current therapies do not simultaneously restore biomechanical support and modulate the pathological intra-articular microenvironment. Here, we developed an injectable dual-network hydrogel that combines thermosensitive poly(N-isopropylacrylamide)-g...
Jinlong Zhang, Xinmeng Zha, Xiang-Xiu Wang et al.
· Biomaterials · 0 citations