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Xiao-Ao Pang

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Open access Sep 2026

Integrated multi-omics, spatial transcriptomics, and functional studies implicate MDK as a mediator of cisplatin-response phenotypes in ovarian cancer

Platinum resistance remains a central barrier to durable disease control in ovarian cancer. In this study, we integrated an ovarian cancer susceptibility GWAS, multi-omics profiling (CPTAC/TCGA), and spatial-single-cell transcriptomics to identify novel therapeutic targets. Cross-platform prioritization nominated m...

Feng Jin, Fang-Xin Li, Xiao-Ao Pang et al. · 0 citations

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