Review
Open access
Oct 2026
Hemoglobin-based oxygen carriers: evolution, translational applications and clinical considerations
Tissue survival depends on adequate oxygen delivery, yet when red blood cell (RBC) transfusions are unavailable or contraindicated, restoring oxygen delivery remains an urgent clinical need. To meet this need, researchers have developed hemoglobin-based oxygen carriers (HBOCs) that transport oxygen via cell-free hemogl...
Huan Tang, Xin-Yi Liu, Hai Zhang et al.
· Frontiers in Medicine · 0 citations