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Xiao-Die Li

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Open access Aug 2026

Transcriptomic profiling of lineage transformation and actionable therapy opportunities in EGFR-mutant non-small cell lung cancer evolving to small cell lung cancer

Neuroendocrine transformation of epidermal growth factor receptor-mutant lung adenocarcinoma (EGFRm LUAD) represents a significant mechanism underlying acquired resistance to EGFR tyrosine kinase inhibitors (TKIs). This histological transformation lacks effective treatments. We comprehensively discussed the treatments...

Hui Yu, Meichen Li, Xiao-Die Li et al. · 0 citations

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