Open access
Sep 2026
Integration of MRI radiomics with immune profiling to predict response to CDK6 inhibitors in high-grade glioma
Background Predictive biomarkers are needed to identify patients with high-grade glioma who benefit from cyclin-dependent kinase 6 (CDK6) inhibition. We hypothesized that an integrated Radiomics–Immune Score (R/I-Score), combining MRI-derived tumor heterogeneity with peripheral immune profiling, would predict progressi...
Jian-Fang Wang, Peng Li, Jin-Hu Li et al.
· Frontiers in Immunology · 0 citations