Review
Open access
Oct 2026
Mitochondrial regulation of tumor-associated macrophage function
Tumor-associated macrophages (TAMs) adapt to hypoxia, nutrient competition, lipid accumulation, and anticancer treatment. Mitochondria contribute to this adaptation through energy metabolism, redox signaling, mitochondrial DNA (mtDNA) sensing, and metabolite-dependent regulation of gene expression. This Review examines...
Jia-Bao Xu, Yong-Tao Liu, Hong-Jie Zhang et al.
· Frontiers in Immunology · 0 citations