Chronic stress leading gut microbiota dysbiosis and neuroinflammation promoted depressive disorder
Chronic stress was known to contribute to gut microbiota dysbiosis and central neuroinflammation, yet the underlying mechanisms remain poorly understood. In this study, forty-eight male C57BL/6 mice were randomly assigned to three groups: control, chronic unpredictable mild stress (CUMS), and CUMS with probiotic interv...